Senior Scientist Biomarker Discovery

Description

Senior Scientist – Biomarker Discovery       

Sector – Drug Discovery

Location – Cambridge

Our client is a Cambridgeshire based early-stage drug development company targeting the ubiquitin pathway for the treatment of neurodegenerative disease, rare mitochondrial diseases and fibrosis. An opportunity has become available for a Senior Scientist to join the Translational Sciences team on a permanent basis to support with the delivery of delivery of in vitro pharmacology / pharmacodynamics studies.

The role:

Working within a small research team you will be responsible for research supporting in vitro pharmacology studies including the discover and development of biomarker assays.

·         Design and development of in vitro assays

·         Development, characterisation and validation of Biomarker assays

·         Identification of biological pathways

·         Evaluate cellular and molecular mechanisms to further understand target biology mechanistics

·         Contribute to biomarker strategy and clinical protocol

Suitable applicants will have:

·         Significant experience with biomarker discovery

·         Experienced in biomarker assay development and validation

·         Postdoctoral or industry experience in target validation for drug discovery.

·         Experience researching and investigating biological mechanisms and disease related pathways

·         MSc, PhD or equivalent experience in a relevant biochemical discipline

·         Experience working with human biospecimens

·         Strong knowledge and practical experience with ELISA, western blotting, flow cytometry, qPCR

The Package:

In return, my client offers the opportunity to work within a dynamic research team in an exciting area of drug discovery. Salary package will be competitive and dependent on experience.